NAME: Tse-Hao Huang (黃則豪)
PERSONAL:
Current Position: Project Assistant Professor
Tel: #7996
E-mail: huang_t_h@mail.ncyu.edu.tw
EDUCATION:
2004-2012 National Yang-Ming University, Taipei, Taiwan
Ph.D., Institute of Biochemistry and Molecular Biology
2002-2004 National Yang-Ming University, Taipei, Taiwan
M.S., Institute of Biochemistry and Molecular Biology
1998-2002 National Tsing Hua University, Hsinchu, Taiwan
B.S., Department of Chemistry
FIELD OF SPECIALTY:
• Analytical Chemistry
• Lateral Flow Immunoassay (LFA) and Rapid Diagnostic Platform Development
• Bioanalytical Chemistry and Biomedical Detection
• Nanoparticle Labeling and Functionalization
EMPLOYMENT:
2026-present Project Assistant Professor
Department of Applied Chemistry, National Chiayi University, Taiwan
2024-2026 R&D Manager
Nanokemy Biotechnology Co., Ltd., Taiwan
2023-2024 Research Specialist
National Yang Ming Chiao Tung University, Taiwan
2017-2022 Postdoctoral Researcher
Linkou Chang Gung Memorial Hospital, Taiwan
2013-2016 R&D Manager
C.J. Biotech Co., Ltd., Taiwan
RESEARCH INTEREST:
1. Development of multifunctional lateral flow immunoassay platforms for food safety and biomedical applications.
2. Nanoparticle labeling, signal enhancement, and multiplex detection for rapid screening.
3. Development and validation of rapid assays for biomarkers, infectious diseases, pesticide residues, and clinical diagnostics.
4. Integration of analytical chemistry, HPLC, mass spectrometry, and image-based quantitative analysis for method comparison and assay validation.
5. Translation of rapid detection technologies from laboratory research to industrial and clinical applications.
TEACHING AND PROFESSIONAL EXPERIENCE:
2024-present R&D Manager
Nanokemy Biotechnology Co., Ltd., Taiwan — biomedical and food-safety assay development and instrumental method comparison/validation
2022-2025 Industry Lecturer
Department of Health and Nutrition, Chang Gung University of Science and Technology — rapid-test principles, sample preparation, and data-analysis practicum (Academic Years 110-113)
2016-2022 Postdoctoral Researcher
Linkou Chang Gung Memorial Hospital, Taiwan — clinical rapid-detection projects including periprosthetic joint infection, CSF leakage, and osteoporosis biomarkers
2024 Journal Reviewer
Analytica Chimica Acta (December 2024)
Prior Research Specialist
National Yang Ming Chiao Tung University — Ministry of Economic Affairs Value Creation Program; commercialization validation for food-safety testing
Prior R&D Manager
C.J. Biotech Co., Ltd. — HbA1c and tumor-marker assay development; familiarity with ISO 13485 processes
SELECTED GRANTS AND PROJECTS:
2025 Principal Investigator, MOEA SBIR (Chiayi City Local Program):
Development and pet-application validation of an innovative nano-antibacterial spray product.
2019 Principal Investigator, MOEA SBIR (Central Program):
Development of a two-in-one pesticide rapid-test reagent for tea.
2022 Key Project Member, Chang Gung Medical Research Project (CMRPG):
Development of a rapid diagnostic system for cerebrospinal fluid leakage.
PROJECT PARTICIPATION:
CMRPG3H0451: Novel multiplex biomarker rapid detection system for diagnosis of spinal disc infection.
CRRPG3H0031-2: Integrated project on new diagnostic and therapeutic approaches for periprosthetic joint infection; Subproject 5: innovative multiplex biomarker rapid detection system.
CMRPG3K0631: Integrated multiplex biomarker rapid detection system for osteoporosis.
MOST epidemic-prevention project: Integrated antigen rapid-test platform development, Chang Gung University Center for Emerging Viral Infections.
CMRPG3L0571: Novel rapid biomarker detection system for diagnosis of cerebrospinal fluid leakage after spinal surgery.
MOEA SBIR 2017: Pesticide immunochromatographic rapid-test platform — chlorfenapyr rapid-test development.
MOEA SBIR 2019: Two-in-one pesticide rapid-test reagent for tea.
MOEA SBIR 2025: Innovative nano-antibacterial spray product development and pet-application validation.
MOEA Value Creation 2.0: Commercialization of rapid and precise pesticide-residue detection technology for food safety.
HONORS AND AWARDS:
2022 Excellent Paper Award
Linkou Chang Gung Memorial Hospital; awarded for the 2022 Analytica Chimica Acta publication on quantitative lateral flow immunoassay for rapid detection and monitoring of cerebrospinal fluid leakage.
REPRESENTATIVE PUBLICATION:
Chou, C. H.; Huang, T. H.; Hsieh, P. C.; Ho, N. Y. J.; Chen, C. A.; Wu, K.; Tsai, T. T. Quantitative lateral flow immunoassay for rapid detection and monitoring of cerebrospinal fluid leakage following incidental durotomy. Analytica Chimica Acta (2022), 339544. Co-first author; recipient of the 2022 Excellent Paper Award from Linkou Chang Gung Memorial Hospital; Impact Factor 5.7; CiteScore Rank Q1 (17/156, 10.90%) in Analytical Chemistry.
LIST OF RESEARCH PUBLICATIONS:
1. Tsai, T. T.; Huang, T. H.; Chang, C. J.; Ho, N. Y. J.; Tseng, Y. T.; Chen, C. F. Antibacterial cellulose paper made with silver-coated gold nanoparticles. Scientific Reports 2017, 7(1), 1-10. (Impact Factor=3.8)
2. Tsai, T. T.; Huang, T. H.; Chen, C. A.; Ho, N. Y. J.; Chou, Y. J.; Chen, C. F. Development a stacking pad design for enhancing the sensitivity of lateral flow immunoassay. Scientific Reports 2018, 8(1), 1-10. (Impact Factor=3.8)
3. Tsai, T. T.; Huang, T. H.; Ho, N. Y. J.; Chen, Y. P.; Chen, C. A.; Chen, C. F. Development of a multiplex and sensitive lateral flow immunoassay for the diagnosis of periprosthetic joint infection. Scientific Reports 2019, 9(1), 1-8. (Impact Factor=3.8)
4. Chen, C. A.; Huang, Y. J.; Ho, N. Y. J.; Huang, T. H.; Tsai, T. T. Smartphone-assisted fluorescent analysis of polyT-Cu-nanoprobes using nucleic acid amplification test for the diagnosis of tuberculosis. Analytical Biochemistry 2021, 630, 114340. (Impact Factor=2.6)
5. Chou, C. H.; Huang, T. H.; Hsieh, P. C.; Ho, N. Y. J.; Chen, C. A.; Wu, K.; Tsai, T. T. Quantitative lateral flow immunoassay for rapid detection and monitoring of cerebrospinal fluid leakage following incidental durotomy. Analytica Chimica Acta 2022, 339544. (Co-first author; Impact Factor=5.7)
6. Chen, C. A.; Chiu, P. Y.; Huang, T. H.; Ho, N. Y. J.; Kao, F. C.; Tsai, T. T. Quantitative lateral flow immunoassay for rapid detection of procollagen type I N-terminal propeptide in the monitoring of osteoporosis treatment. Analytica Chimica Acta 2023, 1239, 340695. (Impact Factor=5.7)
7. 黃則豪、張淑貞、陳頤之。應用於蔬菜檢測的農藥免疫快篩平台：菲克利快篩試劑的開發與應用。長庚科技學刊，2024。
8. Chen, C. A.; Ho, N. Y. J.; Yang, C. C.; Hsiao, H. Y.; Huang, T. H.; Hsieh, M. K.; Lai, P. L.; Tsai, T. T. Smartphone-assisted tuberculosis detection by a smart amplification process and lateral flow immunoassay with a 3D-printed device. Chemical Communications 2025, advance online publication. (In press; Impact Factor=4.2)
PATENTS:
1. Taiwan Invention Patent: Biological Detection Chip (I649563).
2. Taiwan Utility Model Patent: Coronavirus Detection Device (M599910).
3. Taiwan Utility Model Patent Application: Nanoparticles in Aqueous Solution and Their Applications and Equipment (Application No. 115200241; pending).
RESEARCH AND TEACHING VISION:
To establish a multifunctional rapid-screening platform that integrates analytical chemistry, nanoparticle labeling, sensitivity enhancement, multiplex detection, and quantitative readout. The platform will target food-safety and biomedical applications, while research outcomes will be incorporated into analytical chemistry teaching through modular lectures, hands-on experiments, method validation, and student research projects.