國立嘉義大學

國立中正大學化學系博士

六、期刊著作： 校務系統研究成果

1.         Meng-Chun Chi, Bo-Yuan Lu, Yu-Fen Huang, Shih-Wei Wang, Min-Guan Lin, Tzu-Fan Wang* (2023, Feb). Effects of Sodium Dodecyl Sulfate on the Enzyme Catalysis and Conformation of a Recombinant γ-Glutamyltranspeptidase from Bacillus licheniformis. Protein Journal , 42:64–77.

2.         Long-Liu Lin, Bo-Yuan Lu, Meng-Chun Chi, Yu-Fen Huang, Min-Guan Lin, Tzu-Fan Wang* (2022, Mar). Activation and thermal stabilization of a recombinant γ-glutamyltranspeptidase from Bacillus licheniformis ATCC 27811 by monovalent cations. Applied Microbiology and Biotechnology, 106(5-6):1991-2006. MOST 109-2313-B-415-006.

3.         Meng-Chun Chi, Ting-Yu Liao, Min-Guan Lin, Long-Liu Lin*, Tzu-Fan Wang* (2021, May). Catalytic Performance of a Recombinant Organophosphate- Hydrolyzing Phosphotriesterase from Brevundimonas diminuta in the Presence of Surfactants. Catalysts, 11(9), 597.

4.         Meng-Chun Chi, Yu-Fen Huang, Bo-Yuan Lu, Min-Guan Lin, Tzu-Fan Wang*, Long-Liu Lin* (2021, Feb). Magnetic Cross-Linked Enzyme Aggregates of a Transpeptidase-Specialized Variant (N450D) of Bacillus licheniformis γ- Glutamyl Transpeptidase: An Efficient and Stable Biocatalyst for l-Theanine Synthesis. Catalysts, 11(2), 243.

5.         Meng-Chun Chi, Ting-Yu Liao, Min-Guan Lin, Long-Liu Lin*, Tzu-Fan Wang* (2020, Nov). Expression and physicochemical characterization of an N-terminal polyhistidine-tagged phosphotriesterase from the soil bacterium Brevundimonas diminuta. Biocatalysis and Agricultural Biotechnology, 29, 101811-101822.

6.         Meng-Chun Chi, Min-Guan Lin, Yu-Fen Huang, Yi-Yu Chen, Tzu-Fan Wang*, Long-Liu Lin* (2019, Nov). Enzymatic synthesis of L-theanine from L-glutamine and ethylamine by Bacillus licheniformis γ-glutamyltranspeptidase and its mutants specialized in transpeptidase activity.. Biocatalysis and Agricultural Biotechnology, 22, 101393.

7.         Meng-Chun Chi, Huei-Fen Lo, Min-Guan Lin, Yi-Yu Chen, Tzu-Fan Wang*, and Long-Liu Lin* (2019, Sep). Mutational Analysis of a Highly Conserved PLSSMXP Sequence in the Small Subunit of Bacillus licheniformis γ- Glutamyltranspeptidase. Biomolecules.

8.         Tzu-Fan Wang, Huei-Fen Lo, Meng-Chun Chi, Kuan-Ling Lai, Min-Guan Lin and Long-Liu Lin* (2019, Jul). Affinity Immobilization of a Bacterial Prolidase onto Metal-Ion-Chelated Magnetic Nanoparticles for the Hydrolysis of Organophosphorus Compounds. International Journal of Molecular Sciences.

9.         Long-Liu Lin, Meng-Chun Chi, Yuan-Jin Lan, Min-Guan Lin, Tzong-Yuan Juang, Tzu-Fan Wang* (2018, Oct). Facile immobilization of Bacillus licheniformis γ-glutamyltranspeptidase onto graphene oxide nanosheets and its application to the biocatalytic synthesis of γ-l-glutamyl peptides . International Journal of Biological Macromolecules, 117, 1326-1333.

10.     Tzu-Fan Wang, Meng-Chun Chi, Kuan-Ling Lai, Min-Guan Lin, Yi-Yu Chen, Huei-Fen Lo and Long-Liu Lin (2018, Oct). High-level expression and molecular characterization of a recombinant prolidase from Escherichia coli NovaBlue. PeerJ.

11.     Huei-Fen Lo, Meng-Chun Chi, Min-Guan Lin, Yuan-Gin Lan, Tzu-Fan Wang*, Long-Liu Lin* (2018, Sep). Protective Effect of Biological Osmolytes against Heat- and Chaotropic Agent-Induced Denaturation of Bacillus licheniformis γ- Glutamyl Transpeptidase. Journal of Microbiology and Biotechnology, 28(9), 1457–1466.

12.     Meng-Chun Chi, Min-Guan Lin, Yu-Yi Chen, Long-Liu Lin*, Tzu-Fan Wang* (2018, Apr). Functional role of the conserved glycine residues, Gly481 and Gly482, of the γ-glutamyltranspeptidase from Bacillus licheniformis. International Journal of Biological Macromolecules.

13.     Long-Liu Lin, Meng-Chun Chi, Eng-Gin Lan, Min-Guan Lin, Tzong-Yuan Juang, Tzu-Fan Wang* (2017, Nov). Facile immobilization of Bacillus licheniformis γ-glutamyltranspeptidase onto graphene oxide nanosheets and its application to the biocatalytic synthesis of γ-l-glutamyl peptides. International Journal of Biological Macromolecules.

14.     Sin-Yi Jhan, Li-Juan Huang, Tzu-Fan Wang, Ho-Hsuan Chou, and Shu-Hui Chen (2017, Mar). Dimethyl Labeling Coupled with Mass Spectrometry for Topographical Characterization of Primary Amines on Monoclonal Antibodies. Analytical Chemistry.

15.     Min-Guan Lin, Meng-Chun Chi, Yu-Yi Chen, Tzu-Fan Wang, Hui-Fen Lo, Long- Liu Lin (2016, Oct). Site-directed mutagenesis of a conserved Asn450 residue of Bacillus licheniformis γ-glutamyltranspeptidase. International Journal of Biological Macromolecules.

16.     Ku MC, Fang CM, Cheng JT, Liang HC, Wang TF, Wu CH, Chen CC, Tai JH, Chen SH*. (2016) Site-specific covalent modifications of human insulin by catechol estrogens: Reactivity and induced structural and functional changes. Sci Rep. 6:28804.

17.     Lin MG, Chi MC, Chen YY, Wang TF, Lo HF, Lin LL*. (2016) Site-directed mutagenesis of a conserved Asn450 residue of Bacillus licheniformis γ-glutamyltranspeptidase. Int J Biol Macromol. 91:416-425.

18.     Huang LJ, Chiang CW, Lee YW, Wang TF, Fong CC, Chen SH* (2016) Characterization and comparability of stress-induced oxidation and deamidation on vulnerable sites of etanercept products. J Chromatogr B Analyt Technol Biomed Life Sci. S1570-0232(16)30312-9.

19.     Lo HF, Chen BE, Lin MG, Chi MC, Wang TF*, Lin LL* (2016) Gene expression and molecular characterization of a chaperone protein HtpG from Bacillus licheniformis. Int J Biol Macromol. 85:179-91.

20.     Fang CM, Ku MC, Chang CK, Liang HC, Wang TF, Wu CH, Chen SH* (2015) Identification of Endogenous Site-specific Covalent Binding of Catechol Estrogens to Serum Proteins in Human Blood. Toxicol Sci. 148(2):433-42.

21.     Chen JH, Chi MC, Lin MG, Lin LL*, Wang TF* (2015) Beneficial effect of sugar osmolytes on the refolding of guanidine hydrochloride-denatured trehalose-6-phosphate hydrolase from Bacillus licheniformis. Biomed Res Int. 2015:806847.

22.     Chen YY, Lo HF, Wang TF, Lin MG, Lin LL*, Chi MC*. (2015) Enzymatic synthesis of γ-L-glutamyl-S-allyl-L-cysteine, a naturally occurring organosulfur compound from garlic, by Bacillus licheniformis γ-glutamyltranspeptidase. Enzyme Microb Technol. 75-76:18-24.

23.     Lin MG, Chi MC, Chen BE, Wang TF, Lo HF, Lin LL. (2015) Residues Phe103 and Phe149 are critical for the co-chaperone activity of Bacillus licheniformis GrpE. Int J Biol Macromol. 72:724-31.

24.     Wang SH, Wang TF, Wu CH, Chen SH*.(2014) In-depth comparative characterization of hemoglobin glycation in normal and diabetic bloods by LC-MSMS. J Am Soc Mass Spectrom. 25(5):758-66.

25.     Wang TF, Lin MG, Lo HF, Chi MC, Lin LL*. (2014) Biophysical characterization of a recombinant aminopeptidase II from the thermophilic bacterium Bacillus stearothermophilus. J Biol Phys. 40(1):25-40.

26.     Chen BE, Lin MG, Lo HF, Wang TF, Chi MC*, Lin LL* (2013) Introduction of a unique tryptophan residue into various positions of Bacillus licheniformis DnaK. Int J Biol Macromol. 52:231-43. (SCI)

27.     Chen YY, Tsai MG, Chi MC, Wang TF*, Lin LL* (2013) Covalent Immobilization of Bacillus licheniformis γ-Glutamyltranspeptidase on Aldehyde-functionalized Magnetic Nanoparticles. Int. J. Mol. Sci. 14(3):4613-28. (SCI)

28.     Wang TF, Lai NS, Huang KY, Huang HL, Lu MC, Lin YS, Chen CY, Liu SQ, Lin TH, and Huang HB* (2012) Identification and Characterization of the Actin-Binding Motif of Phostensin. Int. J. Mol. Sci. 12:15967-15982. (SCI)

29.     Chen YH, Chi MC, Wang TF, Chen JC, Lin LL* (2012) Preparation of Magnetic Nanoparticles and Their Use for Immobilization of C-Terminally Lysine-Tagged Bacillus sp. TS-23 α-Amylase. Appl Biochem Biotechnol 166:1711-1722. (SCI)

30.     Chuang TT, Ong PL, Wang TF, Huang HB*, Chi MC, Lin LL* (2012) Molecular Characterization of a Novel Trehalose-6-Phosphate Hydrolase, TreA, from Bacillus Licheniformis. Int J Biol Macromol. 50:459-470. (SCI)

31.     Lin YS, Huang KY, Wang TF, Huang HL, Yu HC, Yen JY, Hung SH, Liu SQ, Lai NS, Huang HB* (2011) Immunolocalization of Phostensin in Lymphatic Cells and Tissues. J Histochem Cytochem. 59:741-749.  (SCI)