Current Position:
Associate Research Fellow, Institute of Chemistry, Academia Sinica.
Office Address:
Rm B607, Institute of Chemistry, Academia Sinica, Nangang 115, Taipei, Taiwan
Tel: 02-2789-8652
Fax: 02-2783-1237
E-mail: jthuang@gate.sinica.edu.tw
EDUCATION:
2000-2004 National Taiwan University, Taipei, Taiwan
Ph. D. Chemistry, Biophysical Chemistry
1996-1998 National Tsing Hua University, Hsin-Chu, Taiwan
M. S. Chemistry, Bioorganic Chemistry
1992-1996 National Tsing Hua University, Hsin-Chu, Taiwan
B. S. Chemistry
FIELD OF SPECIALRY:
l Protein Chemistry
l Biophysics
l Biochemistry
EMPLOYMENT:
2014-present Associate Research Fellow
Institute of Chemistry, Academia Sinica, Taiwan
2007-2013 Assistant Research Fellow
Institute of Chemistry, Academia Sinica, Taiwan
2005-2007 Postdoctoral Research Associate
Department of Chemistry, University of Wisconsin-Madison, USA
2004-2005 Postdoctoral Fellow
Institute of Chemistry, Academia Sinica, Taiwan
RESEARCH INTEREST:
1. Explore the process of co-translational protein folding and the roles of chaperones.
2. The normal function of TDP-43 and its role in Amyotrophic Lateral Sclerosis (ALS).
3. The characterization of the aggregation process of TDP-43 and Huntingtin (Htt) in Amyotrophic Lateral Sclerosis (ALS) and Huntington’s disease (HD).
4. The development of therapeutic strategies against neurodegenerative diseases.
HONORS AND AWARDS:
Awards:
2012 Excellent Young Scholar Award
Award received from the Chemical Society Located in Taipei
2012 「科學大師」系列講座講師
Award received in Taipei Municipal University of Education
2005-2007 Taiwan Merit Scholarship
Join program of Taiwan’s Ministry of Education, Council for Economic Planning and Development, and National Science Council.
2004 Best Ph. D. Thesis
Award received from the dean of the Science School, National Taiwan University.
2004 Ph. D. Thesis Excellent Poster Presentation
Award received in Department of Chemistry, National Taiwan University.
2002 The First Place of Poster Competition
Award received in the 8th Symposium of Biophysical Society in Taiwan.
1997 Li-Ching Graduate Thesis Scholarship
Award received from Li-Ching Foundation, Taiwan.
1994 Taoyuan County Government Scholarship
Award received from Taoyuan County Government, Taiwan.
1993 Mr. Jung Ya Wu Educational Scholarship
Award received from Jung Ya Wu Foundation, Taiwan.
Advisor of Student Awards:
2014 Poster Competition Award
Award received from the 19th Biophysical Conference, Advisor of the 1st prize
2013 Oral Competition Award
Award received in 10th TIGP-Molecular Medicine (TIGP-MM) Retreat, 1st Prize
2012 Dissertation award
Award received in Department of Chemistry, National Taiwan University, Advisor of Excellence Award
2012 Poster Competition Award
Award received from the 17th Biophysics Conference, Advisor of the 2nd Prize
2011 Dissertation award
Award received from the Chemical Society Located in Taipei, Advisor of Honorable Mentions
2010 Dissertation award
Award received from the Chemical Society Located in Taipei, Advisor of Excellence Award
Invited Lectures:
(International Symposium)
2016 KAUST-NTU-AS Workshop for Enhancing collaborations on Research and Education in Chemical and Materials Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia
2015 2015-Advances in Peptide and Protein Chemistry: International Chemical Congress of Pacific Basin Societies, Honolulu, Hawaii, USA
2015 分子科學前沿海峽兩岸交流會/中國科學院化學研究所/北京/中國
2014 The 2nd Taiwan-Tohoku University Neuroscience Workshop for Young Scientists : The Brain in Function and Malfunction: a Naurogenetic Approach, The Miyagi-Zao Royal Hotel and Tohoku University, Miyagi, Japan
2014 International Symposium on Nanomedicine Molecular Science, Nagoya University Hospital, Nagoya, Japan
2013 Institute for Protein Research Seminar 2013, Osaka, Japan
2013 2013 Academia Sinica and UC Davis Neuroscience Symposium, University of California, San Francisco, USA
2011 The 11th Tateshina Conference on Organic Chemistry, Nagoya, Japan
2011 The 1st International Kyoto Conference on Organic Nanostructures, Kyoto University, Kyoto, Japan
2010 Pacifichem 2010 Symposium, Hawaii, USA
(Domestic Symposium)
2015 2015-Annual Meeting of Chinese Chemical Society, National Dong Hwa University, Hualien
2015 2015 Taipei International Workshop for Soft Matter and Biophysics, Astronomy-Mathematics Building, National Taiwan University, Taipei, Taiwan
2015 The 6th Taiwan-Japan Symposium on Nanomedicine, Academia Sinica, Taipei, Taiwan
2014 2014 TIGP-NCKU Interdisciplinary Neuroscience Retreat, Tainan, Tainan
2013 2013 The Hebrew University of Jerusalem, Israel - Academia Sinica Bilateral Workshop on Nanoscience and Nanotechnology
2013 2013 Technologies for Medical Diagnosis Therapy Symposium, Academia Sinica, Taiwan
2012 17th Symposium of Biophysical Society in Taiwan, Academia Sinica, Taiwan
2012 Frontiers in Chemistry-A symposium dedicated to the memory of Prof. Ta-shue Chou, Academia Sinica
2011 2011-Annual Meeting of Chemical Society, National Tsing-Hua University, Hsinchu
2011 16th Symposium of Biophysical Society in Taiwan, Hua Lien, Taiwan
2010 2010 Annual meeting of Chinese Chemical Society, Taipei, Taiwan
2009 Frontier of protein aggregation and neurodegenerative disease Symposium, Academia Sinica, Taipei, Taiwan
(Others)
2012 The different faces of intrinsically disordered domains of TDP-43 in Amyotrophic Lateral Sclerosis/Taipei Municipal University of Education
2011 Light up the folding zone within the ribosome tunnel/Sunney Chan Symposium/Academia Sinica, Taiwan
2011 Structural and functional characterization of TDR-DNA binding protein (TDP-43) in Amyotrophic Lateral Sclerosis/National Tsing Hua University
2011 The impact of co-translational protein folding within the ribosome tunnel on chaperone recruitment/ National Dong-Hwa University
2010 Protein misfolding in neuron degenerative disease/National Chia-Yi University
2010 Dance with Chemistry and Biology-From protein misfolding to the new therapeutic strategy against neurodegenerative diseases/National Taiwan University
2010 From TAR-DNA binding protein to Neuron Degenerative Disease/National Taiwan Normal University
2008 Novel biophysical approach to protein folding studies/National Tsing-Hua University
2008 Ultrafast and cotranslational protein folding studies/National Chiao-Tung University
JOURNAL REFEREE:
Acta Biomaterialia
BBA - Molecular Basis of Disease
Biochemistry
Journal of Neurochemistry
Journal of Biological Chemistry
International Journal of Immunopathology and Pharmacology
Journal of the Chinese Chemical Society
List of Research Publications:
JOURNAL ARTICLES:
1. He, R.-Y.; Huang, Y.-C.; Chiang, C.-W.; Tsai, Y.-J.; Ye, T.-J.; Gao, H.-D.; Wu, C.-Y.; Lee, Y.-M.; Huang, J. J.-T.* Characterization and real-time imaging of the FTLD-related protein aggregation induced by amyloidogenic peptides. Chem. Commun. 2015, 51, 8652. (IF: 6.8, ▲: 1)
2. Sun, C.-S. ; Lee, C.-C.; Li, Y-N; Yang S. Y.-C.; Lin, C.-H.; Chang, Y.-C.; He, R.-Y.; Liu, P.-F.; Wang ,C.-H.; Chen, W.; Chern, Y.*; Huang J. J.-T.* Conformational switch of polyglutamine expanded huntingtin into benign aggregates leads to neuroprotective effect. Sci. Rep. 2015, 5, 14992. (IF: 5.6, ▲: 1)
3. Koubek, J.; Chen, Y.-R.; Cheng, R.-P.; Huang, J. J.-T.* Nonorthogonal tRNAcysAmber for protein and nascent chain labeling. RNA 2015, 21, 1672. (IF: 4.9)
4. Sun, C.-S.；Wang, C. Y.-H.；Chen, B.-W.；He, R.-Y.；Wang, C.-H.；Chen, W.；Chern, Y.；Huang, J. J.-T.* The influence of mutations and proline substitutions in TDP-43 C-terminal peptides on its amyloid properties and cellular toxicity. PLoS ONE 2014, 9(8), e103644 (IF: 3.7, ▲: 6)
5. Huang , C.-C.；Bose J.-K.；Majumder P.；Lee K.-H.；Huang, J. J.-T.；Huang J. K.；Shen J. C.-K.* Metabolism and mis-metabolism of the neuropathological signature protein TDP-43. J. Cell Sci. 2014, 127, 3024-3038 (IF: 5.9, ▲: 11)
6. Liu, G. C.-H.；Chen, B. P.-W.；Ye, N. T.-J.；Wang, C.-H.；Chen, W.；Lee, H.-M.；Chan, S. I.；Huang, J. J.-T.* Delineating the membrane-disrupting and seeding properties of the TDP-43 amyloidogenic core. Chem. Commun. 2013, 49,11212-11214. (IF: 6.8, ▲: 5)
(Highlighted in Significant Research Achievements of Academia Sinica 2013)
7. Koubek, J.；Lin, K.-F.；Chen, Y.-R.；Cheng, R.-P.*；Huang, J. J.-T.* Strong anion exchange fast performance liquid chromatography as a versatile tool for preparation and purification of RNA produced by in vitro transcription. RNA 2013, 19,1449-1459 (IF: 5.088, ▲: 12)
8. Huang, Y.-C.；Lin, K.-F；He, R.-Y.；Tu, P.-H.；Koubek, J.；Hsu, Y.-C.；Huang, J. J.-T.* Inhibition of TDP-43 aggregation by nucleic acid binding. PLoS One 2013, 8(5), e64002 (IF: 3.73, ▲: 11)
9. Chang, C.-K.；Wu, T.-H.；Wu, C.-Y.；Chiang, M.-H.；Toh, E.-K.；Hsu, Y.-C.；Lin, K.-F.； Liao, Y.-H.；Huang, T.-H.*；Huang, J. J.-T.* The N-terminus of TDP-43 promotes its oligomerization and enhances DNA binding affinity. Biochem. Biophys. Res. Commun. 2012, 425, 219-224 (IF: 2.406, ▲: 14)
10. Lin, K.-F.；Sun, C.-S.；Huang, Y.-C.；Chan, S.-I.；Koubek, J.；Wu, T.-H.；Huang, J. J.-T.* Cotranslational Protein Folding within the Ribosome Tunnel Influences Trigger-Factor Recruitment. Biophys. J. 2012, 102, 2818-2827. (IF: 3.832, ▲:16)
11. Huang, J. J.-T.; Larsen, R.-W.; Chan, S.-I.* The Interplay of Turn Formation and Hydrophobic Interactions on the Early Kinetic Events in Protein Folding. Chem. Commun. 2012, (Feature Article), 48, 487-497.(IF: 6.718, ▲:7)
12. Chen, K.-H.; Lin, Y.-Y.; Xie, Z.-J.; Tu, P.-H.; Chen, P.-Y.; Liao, T.-Y.; Chen, W.; Wang, C.-H.; Huang, J. J.-T.* Induction of Amyloid Fibrils by the C-Terminal Fragments of TDP-43 in Amyotrophic Lateral Sclerosis. J. Am. Chem. Soc. 2010, 132, 1186-1187. (IF: 11.4, ▲:49) (Highlighted in Significant Research Achievements of Academia Sinica 2010) (Selected in 2010 Science and Technology Yearbook of Republic of China)
13. Hwu, J. R.*; Huang, J. J.-T.; Tsai, F.-Y.; Tsay, S.-C.; Hsu, M.-H.; Hwang, K. C.; Horng, J.-C.; Ho, J. A.; Lin, C.-C. Photochemical activities of N-nitroso carboxamides and sulfoximides as well as their application to DNA cleavage. Chem. Eur. J. 2009, 15, 8742-8750. (Cover Article) (IF: 5.93, ▲:5)
14. Huang, J. J.-T.*; Jhan, J.-W. Ultra-fast and Cotranslational Protein Folding. Natural Sciences Newsletter. 2008, 20, 50-53.
15. Kirchdoerfer, R. N.; Huang, J. J.-T.; Isola, M. K.; Cavagnero, Silvia.* Fluorescence-Based Analysis of Aminoacyl- and Petidyl-tRNA by Low-pH SDS PAGE. Anal. Biochem. 2007, 364, 92-94. (IF: 3.247, ▲:11)
16. Kuo, N. N.-W.; Huang, J. J.-T.; Miksovska, J.; Chen, P.-Y.; Larsen, R.; Chan, S.I.* Effects of turn stability on the kinetics of refolding of a hairpin in β-sheet. J. Am. Chem. Soc. 2005, 127, 48, 16945-16954. (IF: 10.678, ▲:16)
17. Chen, R. P. Y.; Huang, J. J.-T.; Chen, H. L.; Jan, H.; Velusamy, M.; Lee, C. T.; Fann, W. S.; Larsen, R. W.; Chan, S. I.* Measuring the refolding of beta-sheets with different turn sequences on a nanosecond time scale. Proc. Natl. Acad. Sci. U. S. A. 2004, 101, 7305-7310. (IF: 9.737, ▲:56)
BOOK CHAPTER:
1. Chan, S. I. *; Huang, J. J.-T.; Larsen, R. W.; Rock, R. S.; Hansen, K. C. Early kinetic events in protein folding: The development and applications of caged peptides in Dynamic Studies in Biology; Goeldner, M. and Givens. R. (eds), Wiley-VCH GmbH & Co. Germany, 2005, pp 479-494.
POPULAR SCIENCE IN CHINESE:
2. Protein Folding: The journey from ribosome to cellular function (Academia Sinica Newsletter 2012, 1364, 5-8)
蛋白質摺疊:從核醣體到細胞功能的旅程(中央研究院週報2012年1364期-知識天地專刊)
3. Unfreeze Amyotrophic Lateral Sclerosis, Special topics from Neuroscience Program in Academia Sinica (NPAS) (Scientific American-Chinese version 2012, 107, 7-10)
解凍漸凍人(科學人雜誌2011年107期-中央研究院挑戰卓越系列-跨領域攜手合作，揭開神經疾病的奧秘)
PATENT AND TECHNOLOGY TRANSFER
4. Tu P-H, Chen P-Y, Huang J-T, Chern Y, Jang Y-S. Bipartite Molecules and Uses Thereof in Treating Diseases Associated with Abnormal Protein Aggregates, Attorney Docket No.: A0988.70055US00, Client Reference No.: 12A-1021120.
Grant Review:
n Medical Research Council (United Kingdom)
n National Science Council Grants, Taiwan
Invited Talks:
2015 2015-Advances in Peptide and Protein Chemistry: International Chemical Congress of Pacific Basin Societies/Honolulu, Hawaii, USA
2015 分子科學前沿海峽兩岸交流會/中國科學院化學研究所/北京/中國
2015 2015-Annual Meeting of Chinese Chemical Society, National Dong Hwa University/ Hualien
2014 淺談化學 (化學和生物共舞)/ 中央研究院2014院慶演講
2014 TIGP-INS program orientation talk
2013 Institute for Protein Research Seminar 2013/Osaka, Japan
2013 2013 Academia Sinica and UC Davis Neuroscience Symposium, University of California/San Francisco, USA
2012 17th Symposium of Biophysical Society in Taiwan/Academia Sinica, Taiwan
2012 Frontiers in Chemistry-A symposium dedicated to the memory of Prof. Ta-shue Chou/Academia Sinica
2012 The different faces of intrinsically disordered domains of TDP-43 in Amyotrophic Lateral Sclerosis/ Taipei Municipal University of Education
2011 2011-Annual Meeting of Chemical Society/National Tsing Hua University, Hsinchu
2011 11th Tateshina Conference on Organic Chemistry/Nagoya, Japan
2011 The 1st International Kyoto Conference on Organic Nanostructures/Kyoto University, Kyoto, Japan
2011 16th Symposium of Biophysical Society in Taiwan/Hua Lien, Taiwan
2011 Sunney Chan Symposium/Academia Sinica, Taiwan
2011 Structural and functional characterization of TDR-DNA binding protein (TDP-43) in Amyotrophic Lateral Sclerosis/ National Tsing Hua University
2011 Application of Protein Engineering and Evolution to Bio-Industry/Academia Sinica
2011 The impact of co-translational protein folding within the ribosome tunnel on chaperone recruitment/ National Dong-Hwa University
2010 Protein misfolding in neuron degenerative disease/ National Chia-Yi University
2010 Dance with Chemistry and Biology-From protein misfolding to the new therapeutic strategy against neurodegenerative diseases /National Taiwan University
2010 From TAR-DNA binding protein to Neuron Degenerative Disease/National Taiwan Normal University
2010 Pacifichem Symposium/Hawaii, USA
2010 Annual meeting of Chinese Chemical Society/Taipei, Taiwan
2009 The Induction of TDP-43 C-terminal Fragment into Amyloid Fibrils by G294A Mutation in Amyotrophic Lateral Sclerosis/ Frontier of Protein Aggregation and Neurodegenerative Diseases
2008 Novel biophysical approach to protein folding studies/ National Tsing-Hua University
2008 Ultrafast and cotranslational protein folding studies/ National Chiao-Tung University
2008 淺談化學 (化學和生物的圓舞曲:可樂的化學與水母的螢光)/ 中央研究院2008院慶演講
ORGANIZED SYMPOSIUMS:
1. 2015-Advances in Peptide and Protein Chemistry/2015-12-15~2015-12-20/ International Chemical Congress of Pacific Basin Societies, Honolulu, Hawaii, USA (Co-organizer and Section chair).
2. 2013-Biophysics Conference/2013-6-27~2013-6-29/ Institute of Biomedical Sciences, Academia Sinica (Co-organizer and Section chair)
3. 2010-Sunney Chan Lecture /2010-11-26 /Institute of Chemistry, Academia Sinica (Co-Organizer)
4. Frontier of Protein Aggregation and Neurodegenerative Diseases/ 2009-06-04~2009-06-05/ Institute of Chemistry/ Institute of Biochemistry/ Institute of Biomedical Chemistry/ Genomics Research Center/ Institute of Cellular and Organismic Biology/Institute of Molecular Biology (Co-organizer and Section chair)
SERVICE AND TEACHING
Service
1. Instrumentation committee members in Academia Sinica
2. Qualify exam committee members in TIGP-CBMB program, Academia Sinica (2011-)
3. Dormitory committee members in Academia Sinica (2008-)
4. Core members in Neuron Science Program in Academia Sinica (NPAS)(2008-2012)
5. BioPhysics instrumentation user committee members in Academia Sinica (2011-)
6. Academic committee members in Institute of Chemistry, Academia Sinica (2007-)
7. Instrumentation committee members in Institute of Chemistry, Academia Sinica (2011-)
8. Library committee member in Institute of Chemistry, Academia Sinica (2007-)
9. Adjunct professor in Department of Chemistry, National Central University
10. Adjunct professor in Department of Chemical Engineering, National Taiwan University of Science and Technology (2010-)
11. Adjunct professor in National Defense Medical Center (2010-)
12. Adjunct professor in Taipei Municipal University of Education (2012-)
13. Academic committee members in Institute of Chemistry, Academia Sinica (2013-)
Teaching
1. Experimental Molecular Biophysics, TIGP-CBMB program, Academia Sinica (2014) (three lectures)
2. Biochemistry, National Central University (2008-2009) (five lectures)
3. Seminar coordinator, National Central University (2008)
4. Fundamental Chemical Biology and Molecular Biophysics, TIGP-CBMB program, Academia Sinica (2009-2010)(three lectures)
5. The Chemical Biology of Protein Science, National Taiwan University (2010)(two lectures)
6. Application of Protein Engineering and Evolution to Bio-Industry, TIGP-MBAS program, Academia Sinica (2010-2011)(three lectures)
7. Special Topics in Chemical Biology, National Central University (2011)(five lectures)
8. Seminar, TIGP-CBMB program, Academia Sinica (2013)
9. Modern Spectroscopy in Chemistry, Institute of Chemistry, Academia Sinica (2013)(one lecture)
10. Advances in Chemical Biology, National Central University (2013)(six lectures)
11. Special Topics in Chemical Biology, National Central University (2013)(six lectures)
12. Biomolecular Analysis and Engineering, TIGP-MBAS program, Academia Sinica (2013)(two lectures)
POSTER PRESENTATION:
2016 A Simple Way to Determine Stoichiometry of Protein-DNA/RNA Interaction nd the binding mode of TDP-43 RNA Recognition Domains
2015 Synthetic Q/N-rich Polypeptides from TDP-43 Exhibit Amyloidogenic Properties and Induce the Cytoplasmic Aggregation by Microinjection/2015 Annual Meeting of Chemical Society Located in Taipei
2015 Early recognition by SecA targets secretory protein near the ribosome exit tunnel/ Protein synthesis and translational control/Germany
2015 The local and global effects of DnaK and Trigger Factor on ribosome-bound nascent chain dynamics/ Molecular chaperones: From molecules to cells and misfolding diseases/ Greece
2014 The amyloid and prion-like properties of the TDP-43 peptides in Amyotrophic Lateal Sclerosis/ The 2nd Taiwan-Tohoku University Neuroscience Workshop for Young Scientists/ Japan
2014 Synthetic Gluntamine/Asparagine-rich polypeptides from TDP-43 exhibit amyloid properties and induce prion-like aggregation in amyotrophic lateral scelerosis/ The 2nd Taiwan-Tohoku University Neuroscience Workshop for Young Scientists/ Japan
2014 Development of cysteine-specific tRNA and tRNA synthetase for site-specific protein fluorescence labeling in co-translational protein folding studies/25th tRNA Conference/ Greece
2014 Delineating the membrane-disrupting and seeding properties of the TDP-43 amyloidogenic core/ The 19th Biophysics Conference
2014 The modulation of FKBP12 on the mutant Huntintin-induced neurotoxicity and aggregation/ The 19th Biophysics Conference
2013 Modulate polyglutamine protein aggregation by Trigger factor and FKBP12/ NPAS Summer student discussion
2013 Characterization of the aggregation properties of amyloid core in the TDP-43 C-terminal fragments/ NPAS Summer student discussion
2013 C-terminal aggregation-prone domain of neurodegenerative TDP-43 is required for altering ssDNA/RNA structure/ The 18th Biophysics Conference
2013 Characterization of the thermal induced fiber from TDP-43 and its association with single-stranded DNA/ The 18th Biophysics Conference
2013 Inhibition of TDP-43 aggregation by nucleic acid binding/ The 18th Biophysics Conference
2013 Directional binding of nucleic acid to TAR DNA-binding protein (TDP-43) RRM1 domain provides insight into splicing regulation/ The 18th Biophysics Conference
2013 Structure characterization of ATPase-chaperone-preprotein recognition in the secretory pathway/ The 18th Biophysics Conference
2013 Modulate polyglutamin protein aggregation by Trigger factor and FKBP12/ The 18th Biophysics Conference
2012 The influence of molecular chaperones on the mHtt protein aggregation process/2012 Annual Meeting of Chemical Society
2012 Co-translational Protein Folding: The Journey from the Ribosome Tunnel to Cellular Function/The 12th Annual Meeting of the Protein Science Society of Japan
2012 The roles of TDP-43 associated oligonucleotides on its aggregation process/The 12th Annual Meeting of the Protein Science Society of Japan
2012 Characterization of the aggregation properties of amyloid core in the TDP-43 C-terminal fragments/The 17th Biophysics Conference
2012 The impact of mutations in TDP-43 fragments on the formation of amyloid fibers and cellular toxicity/The 17th Biophysics Conference
2012 Co-translational protein folding within the ribosome tunnel influences trigger-factor recruitment/The 17th Biophysics Conference
2012 Observing the oligomerization in living cell model of Huntington’s disease by advanced time-lapse microscopy/NPAS-NCKU Neuroscience Retreat.
2011 Characterize the aggregation process of the mHtt protein in the presence of chaperone/France-Taiwanese Symposium on Neurobiology, IGBMC
2011 The Discovery of the Amyloid Fibrils from the C-terminal Fragments of TDP-43 in Amyotrophic Lateral Sclerosis/The 11th Tateshina Conference on Organic Chemistry , Nagoya, Japan
2011 Study the aggregation properties of TDP-43 in the presence of chaperone and DNA/ The 16th Biophysics Conference
2011 Explore the conformational change and DNA binding mode of TDP-43/The 16th Biophysics Conference
2011 Characterize the biophysical and chemical properties of TDP-43 in ALS/The 16th Biophysics Conference
2011 Characterization of the C-terminal Fragments of TDP-43 in Amyotrophic Lateral Sclerosis/The 16th Biophysics Conference
2010 Identify the specific conformation of the C-terminal Fragments of TDP-43 in Amyotrophic Lateral Sclerosis /NeuroTalk-2010 Conference
2009 Study on Cotranslational Protein Folding within the Ribosomal Exit Tunnel/Joint International Conference of Biophysics and 14th Annual Conference of the Biophysical Society of ROC
2009 Mutation in TDP-43 C-terminal Fragment can Induce Beta-Amyloid Fibril Formation/Joint International Conference of Biophysics and 14th Annual Conference of the Biophysical Society of ROC