國立嘉義大學

一、學歷：
1995 美國羅徹斯特化學博士 U. of Rochester (Advisor: Prof. Richard H. Schlessinger)
1987 清華大學化學研究所
1985 清華大學化學系

二、經歷：
1995/5-1996/6 Rensselaer Polytechnic Institute 博士後研究員 (Adviser: Prof. Arthur G. Schultz)
1996/8-2003/7 朝陽科技大學應用化學系副教授
2003/8-2011/7 嘉義大學應用化學系暨研究所副教授
2011/8- 嘉義大學應用化學系暨研究所教授
2013/2-2018/1 嘉義大學國際事務長
2019/8-2022/7 嘉義大學應用化學系系主任
2020/8-2023/7 嘉義大學理工學院副院長

三、專業領域 / Specialized Area：
有機合成 , 不對稱反應 , 具生物活性小分子合成

四、連絡方式 / Tel or e-mail：
  Tel: 05-2717745
  E-mail: yjli@mail.ncyu.edu.tw

5. [1,2]-Wittig rearrangement of gama-benzyloxy vinylogous urethanes and their synthetic applications

6. 

Synthesis of Biologically active Natural Products.

7. 

六、期刊著作/ Publications (2015-)：校務系統研究成果 

1. Total synthesis of Indolizidine Alkaloids (-)-167B, (-)-209I, and (-)-223A by Using a Common Tricyclic Lactone. Yu-Jang Li,* Chung-Chien Hou, and Kuei-Chen Chang. Eur. J. Org. Chem. 2015, 1659-1663. Supported by MOST-103-2113-M-415-009-. IF = 3.065. (19/59, Chemistry, Organic)

   

    

2. Stereoselective Synthesis of 2,3,4-highly Substituted Oxetanes by Intramolecular C-C Bond Forming Michael Addition, Guo-Ming Ho and Yu-Jang Li*. Chem. Commun, 2016, 52, 12108-12111. DOI: 10.1039/C6CC06857J. Supported by NSC 101-2113-M-415-002, MY2. IF =6.319. (14/157, Chemistry, Multidisciplinary). Reviewed by V. Snieckus, B. P. Schuff on SYNFACTS, 2016, 12, 1242. " Stereoselective Preparation of Substituted Oxetanes"

   

3. Discovery of New Stilbene Antioxidants of the Bio-Elicited Peanut Sprout Powder (BPSP) and Longevity Extension of Mice Fed with BPSP-Supplemented Diets. Robin Y.-Y. Chiou*, Po-Chang Chiu, Ju-Chun Chang, Yu-Jang Li, Chia-Wen Hsieh, Jin-Yi Wu, Shu-Mei Lin, Yun-Lian Lin, Brian B. C. Weng. Food and Nutrition Science, 2017, 8, 141-162.                                                                                                    

   

4. anti-Selective aldol reactions of chiral alcohol-substituted gama-benzyloxyl vinylogous urethanes and the synthesis of 3-benzyloxyl-4-hydroxylalkane-2-ones. Yu-Jang Li*, Chuan-Chung Chung, Pin-Zu Chen. Tetrahedron: Asymmetry 2017, 28, 1573-1581. https://doi.org/10.1016/j.tetasy.2017.10.003.  Supported by MOST-89-2113-M-324-003, MOST-105-2113-M-415-005. IF=2.379. (22/59, Chemistry, Organic)

    
   

5. Tandem [1,2]-Wittig Rearrangement/Lactonization of gama-benzyloxy vinylogous urethanes: Application to the Synthetic studies of Maculalactone A, Planchol C and gama-Lycorane. Guo-Ming Ho, Yu-Jang Li*. Asian J. Org. Chem. 2018,  7, 145-149. http://dx.doi.org.10.1002/ajoc.201700589. Supported by NSC-100-2119-M-415-001. IF=2.788. (20/59, Chemistry, Organic)

   

6. Peroxidase characterization isolated from germinated peanut embryos (GPE) and application of the freezed-dried GPE powder as emzyme source for biomimetic production of delta-viniferin. Po-Chang Chiu, Yu-Jang Li, Robin Y.-Y. Chiou*. J. Procbio. 2018, 66, 97-105. DOI: 10.1016/j.procbio.2017.11.019.
   

     

   
   

7. C-H Functionalization of Amino Alcohols by Osmium Tetroxide/NMO oor TPAP/NMO: Protection Group-Free Synthesis of Indolizidines (-)-223AB and 3-epi-(-)-223AB. Wei-Lun Chen, Lee-Ya Wang, Yu-Jang Li*. Eur. J. Org. Chem. 2020, 103-107.     http://dx.doi.org/10.1002/ejoc.201901494 .
   

   

   
   

8. Inhibition of testosterone-mediated benign prostatic enlargement of orchiectomized Sprague-Dawley rats by diets supplemented with bio-elicited peanut sprout powder (BPSP) and three new BPSP-extracted natural compounds identified.  Cheng, P.-H., P.-C. Chiu, J.-C. Chang, S.-M. Lin, Y.-J. Li, D.-Y. Lo, L.-R. Lai, S.-C. Wu and R. Y.-Y. Chiou*. J. Functional Foods, 2021.79 (2021) 104383.
9. Construction of stereogenic center beta to the N-Pyrrolidinyl moiety via diastereoselective reactions of tricyclic lactones and the synthesis of (−)-Indolizidine 195G. Rou-Jie Huang, Ching-Zong Lou, Wei-Kai Liao, Hsiang-Yu Chuang, Yu-Jang Li*. Tetrahedron 2024, 159,134024.    https://authors.elsevier.com/sd/article/S0040-4020(24)00204-7
10. Concise Synthesis of(-)-isoaltholactone and rac-5-epi-OBn-Goniotriol. Yu-Jang Li,* Cheng-Chiao Li and Chung-Chien Hou. Synth. Commun. 2024, 54(11), 918-926.  https://www.tandfonline.com/eprint/WWCGPJ7YE4B4BFZ9SFEF/full?target=10.1080/00397911.2024.2355474
11. Total Synthesis of Poison Dart-Frog Alkaloids (−)-209D, (−)-209B, (−)-223V, 3-epi-(−)-223AB. Kuei-Chen Chang, Lee-Ya Wang, Cheng-Chiao Li,  Rou-Jie Huang,  Zheng-Feng Zhang, Yu-Fu Liang, Ming-Der Su,* Yu-Jang Li *. ChemistrySelect 2024, 9(33), e202403037. https://onlinelibrary.wiley.com/share/author/NKC8KTZ2CVRKMJYC2XJZ?target=10.1002/ slct. 202403037 
    
12. Presence of Flazin in Miso and Identification of Four Tryptophan-derived ß-Carboline Formed during Fermentation. Yu-Jang Li, Ya-Ping Zhang, Po-Chang Chiu, Sue-Mei Lin, Chuping Lee, Chih-Yu Lo, Wei-Ting Lien and Robin Y.-Y. Chiou,*  J. Agric. Food Chem . 2024, 72, 38, 21065-21076. https://doi.org/10.1021/acs.jafc.4c05855
13. Properties Characterization and Identification of Saponarin and Ribosnarin (apigenin-6-C-ribosyl -7-O-glucoside) Extracted Abundantly from the White-Color Moth Orchid Flowers (Phalaenopsis Hybrids). 

    Po-Chang Chiu¹, Yu-Jang Li², Chih-Yu Lo¹, Shu-Mei Lin¹, Chenwei Huang¹, Robin Y.-Y. Chiou^1*.  Food Nutr. J. 2024, 9: 314. DOI: 10.29011/2575-7091.100314

14. 
    
    

    
    

1. 化學會107年會研討會論文摘要OR-0132, " Protection Free Synthesis of Indolizidine 223AB Analog.", Wei-Lun Chen, Lee-Ya Wang, Yu-Jang Li. 2018年12月8-9日, NSYSU, Kaohsiung.
2. The 20th Tetrahedron Symposium, P1-87, "Oxidative cyclization of cyclic tertiary amines with tethered hydroxy group mediated by osmium tetroxide and the protection free synthesis of indolizidine 223AB." June 18-21, 2019. Bangkok, Thailand.
3. 化學會107年會研討會論文摘要 OR-072. "Catalytic Oxidative Cyclization of Cyclic Aminoalcohols by Osmium tetroxide/NMO or TPAP/NMO and the Protecting Group-Free Synthesis of Indolizidine 223AB and 3-epi-223 AB". Wei-Lun Chen, Lee-Ya Wang, Yu-Jang Li, 2019, Dec 8-12, Taipei, NTU.
4. 化學會2021年會研討會論文摘要 P1-OR-104. "Synthetic Studies Toward BCD Rings of Serratine-Type Alkaloids". Hsiang-Yu Chuang, Yu-Jang Li, 2021, Mar 12-14, Chung-Li, NCU.
5. 化學會2021年會研討會論文摘要 P1-OR-129. "固態聚合物吸附四氧化鋨與四氧化釕催化還氮醇之氧化環化研究". 許晏菱, 陳泓叡 ,李瑜章, 2021, Mar 12-14, Chung-Li, NCU.
6. 化學會2022年會研討會 (IL-Org 1) "Total Synthesis of indolizidine type natural products" Wei-Lun Chen, Chung-Chien Hou, Kui-Chen Chang, Hsiang-Yu Chung, Yu-Jang Li*, 2022, Mar 11-13, Taipei, NTNU.
7. The 15th International Symposium on Organic Reactions (ISOR-15), " Syntthesis and Reactions of a-Aminal-b-Hydroxycycloamines", Hong-Rui Chen, Guan-Yu Lu, Bing-Yi Cai and Yu-Jang Li, 2022, Nov. 3-5, Taichung. 中興大學.
8. 化學會2023年會研討會 (Sun-4-017), " Synthesis and 1,2-rearrangement of a-aminal-b-hydroxycycloamines", Guan-Yu Lu, Bing-Yi Cai and Yu-Jang Li*, 2023, Mar 10-12, Kaohsiung. 高雄大學.
9. 2023生物有機及化學生物學研討會"Total Synthesis of Indolizidine Natural Products, Evolution from Toxic Osmium Tetroxide to Green Photo-Oxidation Process", Wei-Lun Chen, Chung-Chien Hou, Kui-Chen Chang, Guan-Yu Lu, Yu-Jang Li*. 2023, Oct. 14, New Taipei City, 輔仁大學.
10. 化學會2024年會研討會 (O43-4),"Synthesis of nitrogen-containing natural products starting with green photo-oxidative C-H functionalization process", Mar 29-31, 2024, 淡水, 淡江大學.
11. Invited seminar, "Evolution of synthetic methodologies for toxic dart-frog alkaloids", April 15, 2024, 台中, 靜宜大學應化系.

20150721實驗室成員

2015年167B、209I、223A合成慶祝

20151222實驗室成員

20160226實驗室成員

20190515實驗室成員

20230615實驗室成員