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Dr. Yin-Ze SHI Ph.D (https://orcid.org/0000-0001-5142-985X)
Assistant Professor
Tel.: 05-2717768
E-mail: yzshi@mail.ncyu.edu.tw
Goal of Laboratory
Our laboratory analyzes the pathogenicity of pathogens isolated from fish farms, investigates the frequencies of resistant strains and its mechanism, and develops the treatment or prevention methods (vaccines or bacterial phage).
Research interests
(1) Pathogen epidemiological investigation: Using molecular biology technology to identify pathogenic bacterial species including identification of genotypes and serotypes of different strains.
(2) Detection of drug-resistant bacteria: Investigate the frequency of multiple drug resistance (MDR) bacteria and eluate the drug resistance mechanisms through genetic engineering technology.
(3) Disease prevention and treatment: Vaccine development and study of bacterial phage.
Teaching Courses
Molecular Biology Genetics Microbiology General zoology (including experimental course) 、Gene Manipulation and Cell Culture of Animal (plus experimental course)
Education
2017-2021: Ph.D. Department of Applied Biological Science, University of Miyazaki, JAPAN
2013-2016: M.S. Department of Aquaculture, National Taiwan Ocean University, Keelung, Taiwan
2009-2013: B.S. Department of Aquatic Biosciences, National Chiayi University, Chiayi, Taiwan
Professional Experience
2025-present: Assistant Professor, Department of Agricultural Biotechnology, National Chiayi University, Chiayi, Taiwan.
2022-2025: Postdoctoral Research Fellow, National Pingtung University of Science and Technology, Pingtung, Taiwan
2021-2022: Adjunct Assistant Professor, National Kaohsiung University of Science and Technology, Kaohsiung, Taiwan
2021-2022: Assistant Researcher, National Kaohsiung University of Science and Technology, Kaohsiung, Taiwan
Publications
Yin‐Ze Shi, Andre Giovanni, Li‐Wu Cheng, Wen‐Rou Huang, Pei‐Chi Wang, and Shih‐Chu Chen. (2024) Immune response and protection efficacy of formalin‐killed vaccines against Streptococcus iniae in four‐finger threadfin Eleutheronema tetradactylum. Journal of Fish Diseases 47. e14009.
Yin-Ze Shi*, Issei Nishiki, Terutoyo Yoshida. (2023). A Single Point Mutation in the lsa(D) Variant in Fish Pathogenic Lactococcus garvieae Serotype I Which Affects Lincomycin and Related Antibiotics Resistance. Fish Pathology. 58. 48-59. (SCI, Impactor Factor = 0.45; CiteScore Rank: 310/456 = 68%, Animal Science and Zoology)
H-C Chuang†, Yin-Ze Shi†, C-M Cheng, C-Y Pan, A-C Cheng* (2022) Effects of Antrodia camphorata-Supplemented Diets on the Non-Specific Immune Responses and Disease Resistance of Orange-Spotted Grouper (Epinephelus coioides) against Vibrio alginolyticus and Streptococcus iniae. Journal of Marine Science and Engineering, 10, 458. (SCI, Impact Factor = 2.74; CiteScore Rank: 24/68=35.3%, Oceanography) †equal contribution
Yin-Ze Shi*, Terutoyo Yoshida, Atushi Fujiwara, Issei Nishiki (2021) Characterization of lsa(D), a Novel Gene Responsible for Resistance to Lincosamides, Streptogramins A, and Pleuromutilins in Fish Pathogenic Lactococcus garvieae Serotype II. Microbial Drug Resistance, 27, 301-310. (SCI, Impact Factor = 3.431; CiteScore Rank: 38/116= 32.8%, Microbiology (medical)
Yin-Ze Shi, Kitikiew Suwaree, Yu-Yuan Chen, Chih-Hung Hsu, Jiann-Chu Chen* (2020) White shrimp Litopenaeus vannamei hemocytes receiving fucoidan release endogenous molecules that activate and synergize innate immunity in the presence of fucoidan, Aquaculture, 519, 734720. (SCI, Impact Factor = 4.09; CiteScore Rank: 19/224 =8.5%, Aquatic Science)
Yin-Ze Shi, Issei Nishiki*, Soetsu Yanagi, Terutoyo Yoshida (2019) Epidemiological Study on Newly Emerging Lactococcus garvieae Serotype II Isolated from Marine Fish Species in Japan, Fish Pathology, 54, 51-57. SCI, Impact Factor = 0.58; CiteScore Rank: 240/402 =59.7%, Animal Science and Zoology)
Yin-Ze Shi, Jiann-Chu Chen*, Yu-Yuan Chen, Yi-Hsuan Kuo, Hui-Fang Li (2018) Endogenous molecules released by haemocytes receiving Sargassum oligocystum extract lead to downstream activation and synergize innate immunity in white shrimp Litopenaeus vannamei, Fish and Shellfish Immunology, 76, 1-12. (SCI, Impact Factor = 3.298; CiteScore Rank: 12/205 =5.9%, Aquatic Science)