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Shun-Li Wang

Shun-Li Wang 教授近照 
Title: Associate Professor
Education: Ph.D., National Taiwan University
Research Area: Biophysical Chemistry, Laser Spectroscopy
Tel: 886-5-271-7966

e-mail: wangshunli@mail.ncyu.edu.tw  

Research Interests:

1. Bio-sensors monitoring synthesis of chemical compounds

2. Effect of intermolecular hydrogen bonding and protonation on intramolecular charge transfer

3. Characteristics and pharmchemical applications of bio-materials

4. Phase-transfer mechanism of bio-membranes

5. Chemometry

Publications:

(1)     S. L. Wang and T. I. Ho, “Substituent effect on intramolecular charge transfer of styrylheterocycles “ J. Photochem. Photobiol A: Chem ., 2000, 135 , 119.

(2)     S. L. Wang , S. Y. Lin and T. F. Chen, Thermal-dependent hydration process and intramolecular cyclization of lisinopril dihydrate in the solid state. Chem. Pharm. Bull ., 2000 , 48 , 1890.

(3)     S. Y. Lin, S. L. Wang and Y. D. Cheng , Thermally induced structural changes of acetaminophen in phase transition between the solid and liquid states monitored by combination analysis of FT-IR/DSC microscopic system. J. Phys. Chem. Solids, 2000 , 61 , 1889.

(4)     S. L. Wang and T. I. Ho, “Emission spectra studies on the hydrogen-bonding complex between p-Methoxy-2-Styrylquinoline and acids” Spectrochim. Acta, 2001 , 57A , 361.

(5)     S. L. Wang , S. Y. Lin and T. F. Chen, Reaction kinetics of solid-state cyclization of enalapril maleate isothermally investigated by microscopic FT-IR/DSC system. Chem. Pharm. Bull ., 2001 , 49 , 402.

(6)     S. L. Wang , S. Y. Lin, T. F. Chen and C. H. Chuang, Solid-state Trans-Cis isomerization of captopril determined by Thermal FT-IR microspectroscopy. J. Pharm. Sci . 2001 , 90 , 1034.

(7)     S. L. Wang , S. Y. Lin and Y. S. We, Metastable transformation of acetaminophen polymorphs investigated by thermal FT-IR microspectroscopy. Chem. Pharm. Bull ., 2002, 50 , 153.

(8)     S. L. Wang , C. H. Chung and S. Y. Lin, Metal-lisinopril complex: PH-dependent coordination investigated by attenuated total reflection/Fourier transfer infrared spectroscopy. Chem. Pharm. Bull ., 2002, 50 , 78.

(9)     S. Y. Lin, S. L. Wang , T. F. Chen TF and L. T. Lee, Solid-state diketopiperazine formation of enalapril via intramolecular cyclization studied by simultaneous FTIR/DSC microscopic system. Eur. J. Pharm. Biopharm . 2002, 54, 249.

( 10 ) S. L. Wang , T.C. Lee and T. I. Ho, Excited state proton transfer and steric effect on the hydrogen bonding interaction of styrylquinoline system. J. Photochem. Photobiol A: Chem ., 2002, 151, 21-26

(11)T. C. Hu, S. L. Wang , T. F. Chen and S. Y. Lin, “Hydration induced proton transfer in the solid state of norfloxacin” J. Pharm. Sci . 2002, 91, 1351 .

(12). Y. S. Wei, S. Y. Lin, S. L. Wang , M. J. Li and W. T. Cheng ” Fourier transform IR attenuated total reflectance spectroscopy studies of cysteine-induced changes in secondary conformations of bovine serum albumin after UV-B irradiation.” Biopolymers . 2003 , 72, 345-51

(13) S. L. Wang , Y. S. Wei and S. Y. Lin “Similarity Subtractive Method Used to Get Infrared Spectra of Proteins in Aqueous Solution” Vib. Spectrosc . 2003, 31, 313.

(14) C . Y. Chen, J. H. Ho, S. L. Wang and T. I. Ho “Excimer and intramolecular charge transfer chemiluminescence from electrogenerated ion radicals of donor-acceptor stilbenoids” Photochem. Photobiol. Sci . 2003, 2, 1232-1236..

(15) T. I. Ho, T. C. Lee, J. H. Ho and S. L. Wang “ The photonation and hydrogen bonding interaction in N,N-dimethyl-4-(phenylimino-methyl)-aniline system” Tamkang J. Sci. Eng . 2003 , 6, 37.

(16) S. L. Wang , R. M. Epand, “ Factors Determining Pressure Perturbation Calorimetry Measurements: Evidence for the Formation of Metastable States at Lipid Phase Transitions ” Chem Phys. Lipids 2004, 129, 21-30.

(17). S. Y. Lin, Y. S. Wei, M. J. Li and S. L. Wang “Effect of ethanol or/and captopril on the secondary structure of human serum albumin before and after protein binding” Eur. J. Pharm. Biopharm . 2004 , 57, 457-464.

(18) S. Y. Lin, K. H. Chen, M. J. Li, W. T. Cheng and S. L. Wang ” Evidence of octacalcium phosphate and Type-B carbonated apatites deposited on the surface of explanted acrylic hydrogel intraocular lens” J Biomed Mater Res . 2004 , 70B, 203-8.

(19) S. L. Wang , Shan-Yang Lin, Ting-Fang Chen and Wen-Ting Cheng “ Eudragit E Accelerated the Diketopiperazine Formation of Enalapril Maleate Determined by Thermal FTIR Microspectroscopic Technique ” Pharm. Res . 2004, 21 . 2127.

(20) S. L. Wang, S.Y. Lin, M.J. Li, Y.S. Wei, T.F. H.” Temperature effect on the structural stability, similarity, and reversibility of human serum albumin in different states” Biophys. Chem. 2005 , 114 , 205.

(21) S. L. Wang , Guo-Yi Gao, Tong-Ing Ho, Li-Yu Yang “Excited-State Proton Transfer and Excited-state De-hydrogen Bonding of the Push-Pull Styryl System” Chem. Phys. Lett . 2005 , 415, 217-222.

(22) S. L. Wang , Tzu-Wei Yeh, Tong-Ing Ho “ Photophysics and Excited-State Proton Transfer of 2'-hydroxy-2-trans-styrylquinoline” Chem. Phys. Lett . 2005 , 418, 393-7.

(23) Chen, W. T., Lin, S. Y., & Wang, S. L. (2008). Differential Scanning Calorimetry with Curve-Fitting Program Used to Quantitatively Analyze the Polymorphic Transformation of Famotidine in the Compressed Compact. Drug Dev Ind Pharm, 34, 1368-1375.

(24) Cheng, W. T., Wang, S. L., & Lin, S. Y. (2008). Solid-state interaction study on the captopril/lubricants systems accelerated by grinding process. J. Phys. Chem. Solid, 69, 1007-1016.

(25) Wang, S. L., Lin, J. M., Shu, S. E., & Chern, C. Y. (2010). Influences of protonation and hydrogen bonding on intramolecular charge transfer compounds possessing different spacers. Journal of Photochemistry and Photobiology A: Chemistry, 210, 54–60.

(26) S. L. Wang*, Y. C. Wong, W. T. Cheng and S. Y. Lin (2011). A continuous process for solid-state dehydration, amorphization and recrystallization of metoclopramide HCL monohydrate studied by simultaneous DSC-FTIR microspectroscopy. J therm. anal. Calorim, 104, 261–264.

(27) W. T. Cheng, S. L. Wang* and S. Y. Lin (2011). Thermal FT-IR microspectroscopy for rapid detection of solid-state ion-exchange reaction between metoclopramide HCl monohydrate and potassium bromide. Analyst 136, 1036–1040.

(28) Shan-Yang Lin, Shun-Li Wang* (2012). Advances in simultaneous DSC–FTIR microspectroscopy for rapid solid-state chemical stability studies: Some dipeptide drugs as examples. Adv. Drug Deliv. Rev. 64, 461–478.

(29) Po-Chun Hsu, Hong-Liang Lin, Shun-Li Wang*, Shan-Yang Lin* (2012). Solid-state thermal behavior and stability studies of theophylline–citric acid cocrystals prepared by neat cogrinding or thermal treatment. J. Solid State Chem. 192, 238–245.