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吳青芬 Wu, Ching Fen 助理教授 |
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最高學歷：德國美茵茲大學（Johannes Gutenberg-Universität Mainz）藥學暨生物化學研究所博士 MAIL：cfwu@mail.ncyu.edu.tw 電話：05-2732960 傳真：05-2732917 |
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國立嘉義大學獸醫學系助理教授 (2019/08迄今 財團法人農業科技研究院動物科技研究所研究員 財團法人國家衛生研究院蚊媒病中心博士後研究員 高雄醫學大學醫學院傳染病及癌症研究中心博士後研究員 行政院國家科學委員會與德國學術交流總署（NSC/DAAD）博士班研究生赴德研究訪問三明治計畫 |
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研究 |
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天然物分子藥理、實驗室診斷檢測開發 |
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獸醫臨床病理學及實習、獸醫藥理學、獸醫毒理學、營養疾病學、動物福利學、獸醫免疫學、獸醫細菌學 |
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期刊論文: 1. Lo DY, Kuo HC, Twu NC, Wu CF*. Case report: Enterococcus hirae Infection in
Suckling Pigs. Taiwan Vet. J. 2022
May; 47(3). DOI: 10.1142/S1682648522500032. 2. Lo DY, Yeh TL, Kuo HC, Wu CF*. Development of
Multilocus Sequence Typing (MLST) of Actinobacillus
pleuropneumniae. Taiwan Vet. J.
2022 May; 47(3). DOI: 10.1142/S16826485 22720015. 3. Chang GR, Liu HY, Yang WC, Wang CM, Wu CF, Lin JW, Lin WL, Wang YC,
Lin TC, Liao HJ, Hou PH, Chan CH, Lin CF. Clozapine worsens glucose
intolerance, nonalcoholic fatty liver disease, kidney damage and retinal
injury and increases renal reactive oxygen species production and chromium
loss in obese mice. Int. J. Mol. Sci. 2021, 22:6680. 3. Chang GR, Hsieh WT, Chou LS, Lin CS, Wu CF, Lin JW, Lin WL, Lin TC,
Liao HJ, Kao CY, Lin CF. Curcumin improved glucose intolerance, renal injury,
and nonalcoholic fatty liver disease and decreased chromium loss through
urine in obese mice. Processes. 2021, 9: 1132. 4. Wu CF, Chen CH, Wu CY, Lin CS, Su YC, Wu CF, Tsai HP, Fan PS, Yeh
CH, Yang WC, Chang GR. Quinolone and organophosphorus insecticide residues in
bivalves and their associated risks in Taiwan .
Molecules. 2020, 25: 3636. 5. Chang CP, Hou PH, Yang WC, Wu CF, Chang CC, Tsai MY, Tsai
HP, Lin CT, Xue YJ, Wang JH, Chang GR. Analytical detection of sulfonamides
and organophosphorus insecticide residues in fish in Taiwan. Molecules. 2020, 25: 1501. 6. Chang KC, Chou HY, Chen MY, Wu CF, Chen CC, Hung SW. Investigation
of folate and folic acid metabolite by validated microbiological methods and
LC-MS/MS: quantification in chicken eggs. Biomed. J. Sci. & Tech. Res. 2019,
17: 12498-12501. 7. Fang CC*, Wu CF*,
Liao YJ, Huang SF, Chen M, Chen YM. AAV serotype 8-mediated liver specific
GNMT expression delays progression of hepatocellular carcinoma and prevents carbon
tetrachloride-induced liver damage. Sci. Rep., 2018, 8:13802.
(*:equal contribution) 8. Hong C, Cao J, Wu CF, Kadioglu O, Schüffler A,
Kauhl U, Opatz T, Thines E, Efferth T. The Chinese herbal formula Free and
Easy Wanderer ameliorates oxidative stress through Keap1-Nrf2/HO-1
pathway. Sci. Rep. 2017, 7:11551. 9. Hong C, Schüffler A, Kauhl U,
Cao J, Wu CF, Opatz T, Thines E, Efferth
T. Identification of NF-κB as determinant of posttraumatic stress
disorder and its inhibition by the Chinese herbal remedy Free and Easy
Wanderer. Front. Pharmacol.2017, 8:181. 10. Seo EJ, Wu CF,
Ali Z, Wang YH, Khan SI, Walker LA, Khan IA, Efferth T. Both Phenolic
and Non-phenolic Green Tea Fractions Inhibit Migration of Cancer Cells. Front.
Pharmacol. 2016, 7:398. 11. Efferth T, Banerjee M, Paul
N, Abdelfatah S, Arend J, Elhassan G, Hamdoun S, Hamm R, Hong C, Kadioglu O,
Naß J, Ochwangi D, Ooko E, Ozenver N, Saeed M, Schneider M, Seo EJ, Wu
CF, Yan G, Zeino M, Zhao Q, Abu-Darwish M, Andersch K, Alexie G,
Bessarab D, Bhakta-Guha D, Bolzani V, Dapat E, Donenko F, Efferth M, Greten
H, Gunatilaka L, Hussein A, Karadeniz A, Khalid H, Kuete V, Lee IS, Liu L,
Midiwo J, Mora R, Nakagawa H, Ngassapa O, Noysang C, Omosa L, Roland FH,
Shahat A, Saab A, Saeed E, Shan L, Titinchi S. Biopiracy of natural products
and good bioprospecting practice. Phytomedicine. 2016, 23:
166-173. 12. Wu CF,
Seo EJ, Klauck SM, Efferth T. Cryptotanshinone deregulates unfolded protein
response and eukaryotic initiation factor signaling in acute lymphoblastic
cells. Phytomedicine 2016, 23: 174-180. 13. Wu CF,
Bohnert S, Thines E, Efferth T. Cytotoxicity of the root extract of Salvia
miltiorrhiza against multidrug-resistance cancer cells. Am. J. Chin.
Med. 2016, 44: 871-894. 14. Wu CF,
Karioti A, Rohr D, Bilia AR, Efferth T. Production of rosmarinic acid and
salvianolic acid B from callus culture of Salvia miltiorrhiza with
cytotoxicity towards acute lymphoblastic leukemia cells. Food Chem. 2016,
201: 292-297. 15. Wu CF,
Klauck SM, Efferth T. Anticancer activity of cryptotanshinone on acute
lymphoblastic leukemia cells. Arch. Toxicol. 2016, 90: 2275-2286. 16. Wu CF, Hong C,
Klauck SM, Lin YL, Efferth T. Molecular mechanisms of rosmarinic acid in
acute lymphoblastic leukemia cells. J. Ethanolpharmacol. 2015,
176:55-68. 17. Wu CF, Efferth T.
Miltirone induces G2/M cell cycle arrest and apoptosis in CCRF-CEM acute
lymphoblastic leukemia cells. J. Nat. Prod. 2015, 78: 1339-1347. 18. Dörsam B,Wu CF,, Efferth T,
Kaina B, Fahrer J. The eucalyptus oil ingredient 1,8-cineol induces oxidative
DNA damage. Arch. Toxicol. 2015, 89: 797-805. 19. Hamm R, Chen YR, Seo EJ, Zeino M, Wu
CF, Müller R, Yang NS, Efferth T. Induction of cholesterol
biosynthesis by archazolid B in T24 bladder cancer cells. Biochem.
Pharmacol. 2014, 91:18-30. 20. Wu CFLin YL, Huang
YT. Hepatitis C virus core protein stimulates fibrogenesis in hepatic
stellate cells involving the obese receptor. J. Cell. Biochem. 2013,
114: 541-550 21. Lin YL, Wu CF,
Huang, YT. Effects of Rhubarb on migration of rat hepatic stellate cells.J.
Gastroenterol. Hepatol. 2009, 24: 453-61 22. Lin YL, Wu CF, Huang, YT. Phenols from the roots
of Rheum palmatumattenuates chemotaxis in rat hepatic stellate
cells.Planta Med. 2008, 74: 1246-52. 23. Hsu YC, Chiu YT, Cheng CC, Wu
CF, Lin YL, Huang, YT. 2005. Antifibrotic effects of tetrandrine on
hepatic stellate cells and rats with liver fibrosis. J.
Gastroenterol. Hepatol, 2007, 22: 99-111. 24. Hsu YC, Chiu YT, Lee CY, Wu
CF, Huang, YT. Antifibrotic effects of tetrandrine on bile duct
ligated rats. Can. J. Physiol. Pharmacol. 2006, 84: 967-976. 專書著作: 1. Wu CF, Efferth T.
(2017) Anticancer activity of Salvia miltiorrhiza secondary metabolites, in
Salvia Biotechnology (eds V. Georgiev and A. Pavlov), Springer International
Publishing. pp. 179-208. Doi: 10.1007/978-3-319-73900-7_5 2. Seo EJ, Wu CF,
Greten HJ, Efferth T. (2015) Epidermal growth factor receptors and downstream
signalling pathways as cancer treatment targets for medicinal plants, in
Ethnopharmacology (eds M. Heinrich and A. K. Jäger), John Wiley & Sons,
Ltd, Chichester, UK. pp.169-178. Doi:10.1002/9781118930717.ch16 |
